Introduction.Although rare, cholesteatoma can develop as a late complication of cochlear implantation.The electrode array may then be exposed in the external auditory canal surrounded by cholesteatoma debris.Case Report.The cochlear implant of a child was inadvertently explanted by a clinician during a routine aural toilet procedure.The child had p
Deep mutational scanning reveals transmembrane features governing surface expression of the B cell antigen receptor
B cells surveil the body for foreign matter using their surface-expressed B cell antigen receptor (BCR), a tetrameric complex comprising a membrane-tethered antibody (mIg) that binds antigens and a signaling dimer (CD79AB) that conveys this interaction to the B cell.Recent cryogenic electron microscopy (cryo-EM) structures of IgM and IgG isotype BC
Planning Uncertainty: Creating an Artefact Density Index for North Yorkshire, England
Portable antiquities (sometimes known as small finds or chance finds) are often recorded within most Historic Environment Records to a spurious level of precision.For example, finds located only within a parish, or general area, are often mapped within GIS systems to exact points.Similarly, finds known only to the nearest kilometre square are usual